Stress and cAMP-CREB cascade: Implications for Stress-Related Psychiatric Disorders
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چکیده
منابع مشابه
DSM-5 Trauma and Stress-Related Disorders: Implications for Screening for Cancer-Related Stress
DSM-5: TrauMa anD STreSS-relaTeD DiSorDerS In DSM‐5, disorders which are precipitated by specific stressful and potentially trau‐ matic events are included in a new diag‐ nostic category, “Trauma and Stress‐Related Disorders,” which includes both Adjustment Disorders (ADs) and PTSD (5). Friedman and his colleagues (6) assert that there is heuristic value in grouping this set of dis‐ orders in a...
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A deeper understanding of the pathomechanisms leading to stress-related psychiatric disorders is important for the development of more efficient preventive and therapeutic strategies. Epidemiological studies indicate a combined contribution of genetic and environmental factors in the risk for disease. The environment, particularly early life severe stress or trauma, can lead to lifelong molecul...
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Repeated, extreme, or traumatic stressors can elicit pathological effects leading to many negative physical and psychological outcomes. Stressors can precipitate the onset of psychiatric diseases, or exacerbate pre-existing disorders including various anxiety and mood disorders. As stressors can negatively impact human psychiatric health, it is essential to identify neurochemicals that may conf...
متن کاملThe -Endorphin Role in Stress-Related Psychiatric Disorders
Long known for its anti-nociceptive effects, the opioid -endorphin is also reported to have rewarding and reinforcing properties and to be involved in stress response. In this manuscript we summarize the present neurobiological and behavioral evidence regarding the role of -endorphin in stress-related psychiatric disorders, depression and PTSD. There is existing data that support the importance...
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Posttraumatic stress disorder (PTSD) is a prevalent anxiety disorder. Symptoms present shortly after an exposure to a traumatic event, abate with time in the majority of those who initially express them, and leave a significant minority with chronic PTSD. PTSD may be treated with pharmacotherapy or psychotherapy. Treatment of the early expressions of the disorder constitutes a separate domain o...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2000
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.116.supplement_107